Polypoidal choroidal vasculopathy

This is a sub-type of age-related macular degeneration that needs indocyanine green angiography for diagnosis. The innner choroidal vascular network of vessels has a polyp-like structure. It is thought to be more common in Asians (representing up to 20% of AMD) than in Caucasians. In Japanese patients, about 40% of patients with PCV had classic choroidal neovascular membranes on fluorescein angiography and were therefore suitable for treatment with photodynamic therapy (PDT).  These patients did better than patients with AMD without PCV with PDT therapy (mean gain of 7 letters compared to mean loss of 7 letters in patients without PCV at one year) – from Ophthalmology 2008;115:141-146